Glucosamine: Will It Help Your Joint Pain?

Glucosamine is a protein that occurs naturally in the cartilage of joints. Taking this substance orally in the form of a supplement is thought to help slow the progression of arthritis and relieve pain and swelling for some people.

Does Glucosamine Work?
There is some evidence to suggest it might. In the United States, glucosamine is considered a nutritional supplement, not a medication. It’s not regulated by the Food and Drug Administration, nor is it subject to the same lengthy, scientific study as over-the-counter and prescription drugs.

Though there has been little study on glucosamine in the United States, European research suggests that it may help reduce joint pain and swelling. In fact, the German counterpart to the FDA has endorsed glucosamine sulfate as an alternative to arthritis medications like aspirin, ibuprofen and prescription-strength drugs. Glucosamine may relieve arthritis for many people without causing stomach upset or other side effects associated with these traditional medications.

There is a growing consensus in the medical community that, while more scientific study is needed, glucosamine probably won’t hurt you, and it may even help. If you’re thinking of trying glucosamine, here are some things to remember:

• Talk to your doctor first. Though the FDA does not consider glucosamine a drug, it can interact with other medications or affect some people adversely. Consult with your physician before you take glucosamine and, as with any therapy, receive ongoing evaluation by your doctor.


• Know what you’re buying. Different types of glucosamine are available. Be aware that there can be substantial variation in efficacy and quality among the brands. The glucosamine that has been studied the most broadly is glucosamine sulfate. Combinations sold with chondroiton or hydrochloride have not been widely tested and, initially, have not had the positive results of glucosamine sulfate.


• It doesn’t work for everybody. While some people report symptom relief, others report no effect at all. If you try glucosamine sulfate for your degenerative arthritis, you may not experience results for several weeks or months, so you need to be patient. Also, keep in mind that your symptoms will return once you stop taking glucosamine.


• It won’t prevent or cure arthritis. Even if you experience benefits from glucosamine, you may still need to take medications or undergo other treatments as prescribed by your doctor. More importantly, you need to remember that a program of regular, aerobic exercise and weight control remain the most significant factors in preventing and treating arthritis.